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Успехи молекулярной онкологии

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Морфологическая классификация нэйроэндокринных новообразований пищеварительной системы: современное состояние проблемы и нерешенные вопросы

https://doi.org/10.17650/2313-805X-2016-3-3-56-66

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Аннотация

Нейроэндокринные опухоли образуют разнородную группу злокачественных эпителиальных новообразований, диагностика которых основывается на особенностях гистологической структуры и иммуногистохимического профиля. В классификации Всемирной организации здравоохранения (2010) для нейроэндокринных новообразований пищеварительной системы были определены основные категории, номенклатура, критерии градации и стадирования. При этом накопленные данные демонстрируют ряд важных патоморфологических противоречий в подходе к классификации. В данном обзоре мы остановимся на некоторых общих особенностях нейроэндокринных новообразований, их классификации, морфологических и биологических различиях основных категорий, наиболее важных иммуногистохимических маркерах.

Об авторе

В. В. Делекторская
ФГБУ «Российский онкологический научный центр им. Н. Н. Блохина» Минздрава России; Россия, 115478, Москва, Каширское шоссе, 24
Россия


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Для цитирования:


Делекторская В.В. Морфологическая классификация нэйроэндокринных новообразований пищеварительной системы: современное состояние проблемы и нерешенные вопросы. Успехи молекулярной онкологии. 2016;3(3):56-66. https://doi.org/10.17650/2313-805X-2016-3-3-56-66

For citation:


Delektorskaya V.V. Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversies. Advances in molecular oncology. 2016;3(3):56-66. (In Russ.) https://doi.org/10.17650/2313-805X-2016-3-3-56-66

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ISSN 2313-805X (Print)
ISSN 2413-3787 (Online)