Advances in Molecular OncologyAdvances in Molecular OncologyУспехи молекулярной онкологии2313-805X2413-3787Publishing House ABV Press16110.17650/2313-805X-2018-5-3-8-16REVIEW ARTICLESОБЗОРНЫЕ СТАТЬИClinical, morphological, and molecular genetic predictors of metastatic lesions in the regional lymph nodes in breast cancerКлинико-морфологические и молекулярно-генетические предикторы метастатического поражения регионарных лимфатических узлов при раке молочной железыhttps://orcid.org/0000-0002-7499-2650DergunovaYu. A.ДергуноваЮ. А.
Russian Federation
dergunova.yu@mail.ruhttps://orcid.org/0000-0003-0096-7126PodionovV. V.РодионовВ. В.
Russian Federation
https://orcid.org/0000-0001-8351-8152BozhenkoV. K.БоженкоВ. К.
Russian Federation
https://orcid.org/0000-0001-9666-6875KometovaV. V.КометоваВ. В.
Russian Federation
https://orcid.org/0000-0002-4489-7660DardykM. V.ДардыкМ. В.
Russian Federation
Institute of Medicine, Ecology, and Physical Culture, Ulyanovsk State UniversityИнститут медицины, экологии и физической культуры ФГБОУ ВО «Ульяновский государственный университет»ФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии им. акад. В.И. Кулакова» Минздрава РоссииV.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of RussiaФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии им. акад. В.И. Кулакова» Минздрава РоссииRussian Scientific Center of Roentgen Radiology, Ministry of Health of RussiaФГБУ «Российский научный центр рентгенорадиологии» Минздрава России15092018538161011201810112018Copyright ©; 2018, Dergunova Y.A., Podionov V.V., Bozhenko V.K., Kometova V.V., Dardyk M.V.Copyright ©; 2018, Дергунова Ю.А., Родионов В.В., Боженко В.К., Кометова В.В., Дардык М.В.2018Dergunova Y.A., Podionov V.V., Bozhenko V.K., Kometova V.V., Dardyk M.V.Дергунова Ю.А., Родионов В.В., Боженко В.К., Кометова В.В., Дардык М.В.https://creativecommons.org/licenses/by/4.0https://umo.abvpress.ru/jour/article/view/161

Despite the sufficient amount of data accumulated in the literature, there are still no factors, on the basis of which it would be possible to estimate the regional lymph nodes status in breast cancer with a high degree of accuracy. The review presents literature data relating to the influence of clinicopathological, molecular-biological and genetic characteristics of primary tumor on lymph node metastases. Data of 66 foreign and Russian articles are included.

Несмотря на достаточное количество накопленных данных, все еще не выделены факторы, на основании которых можно было бы с высокой степенью достоверности судить о статусе регионарных лимфатических узлов при раке молочной железы. В обзоре представлены данные литературы, касающиеся влияния клинико-морфологических, молекулярно-биологических и генетических характеристик первичной опухоли на метастатическое поражение регионарных лимфатических узлов. В работу включены данные 66 зарубежных и отечественных статей.

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