Advances in Molecular OncologyAdvances in Molecular OncologyУспехи молекулярной онкологии2313-805X2413-3787Publishing House ABV Press16910.17650/2313-805X-2018-5-3-83-91RESEARCH ARTICLESЭКСПЕРИМЕНТАЛЬНЫЕ СТАТЬИAbility to form duplexes as a factor of intracellular microRNA distributionСпособность к формированию дуплексов как фактор внутриклеточного распределения микроРНКhttps://orcid.org/0000-0003-1660-0898KuzmichevS. A.КузьмичевС. А.
Russian Federation
kuzs2005@mail.ruhttps://orcid.org/0000-0003-0766-163XKomelkovA. V.КомельковА. В.
Russian Federation
https://orcid.org/0000-0001-8837-7969TchevkinaE. M.ЧевкинаЕ. М.
Russian Federation
Research Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaНИИ канцерогенеза ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава РоссииA. I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of RussiaФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России150920185383911011201810112018Copyright ©; 2018, Kuzmichev S.A., Komelkov A.V., Tchevkina E.M.Copyright ©; 2018, Кузьмичев С.А., Комельков А.В., Чевкина Е.М.2018Kuzmichev S.A., Komelkov A.V., Tchevkina E.M.Кузьмичев С.А., Комельков А.В., Чевкина Е.М.https://creativecommons.org/licenses/by/4.0https://umo.abvpress.ru/jour/article/view/169

microRNAmiRNA duplexminimal free energyintracellular localizationмикроРНКдуплекс миРНКминимальная свободная энергиявнутриклеточная локализацияKatohin A.V., Kuznetsova T.N., Omel’yanchuk N.A. MiRNA – new regulators of gene activity in eukaryotes. Vesytik VOGiS = Bulletin VOGiS 2006;10(2):241–72. (In Russ.).Катохин А.В., Кузнецова Т.Н., Омельянчук Н.А. МиРНК – новые регуляторы активности генов у эукариот. Вестник ВОГиС 2006;10(2):241–72.Jeffriesa C.D., Fried H.M., Perkins D.O. Nuclear and cytoplasmic localization of neural stem cell microRNAs. RNA 2011;17(4):657–86. DOI: 10.1261/rna.2006511. PMID: 21363885.Liang H., Zhang J., Zen K. et al. Nuclear microRNAs and their unconventional role in regulating non-coding RNAs. Protein Cell 2013;4(5):325–30. DOI: 10.1007/s13238-013-3001-5. PMID: 23584808.Park C.W., Zeng Y., Zhang X. et al. Mature microRNAs identified in highly purified nuclei from HCT116 colon cancer cells. RNA Biol 2010;7(5):606–14. PMID: 20864815.Villarroya-Beltri C., Gutiérrez-Vázquez C., Sánchez-Cabo F. et al. Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs. Nature Communications 2013;4(2980):1–10. DOI: 10.1038/ncomms3980. PMID: 24356509.Lai E.C., Wiel C., Rubin G.M. Complementary miRNA pairs suggest a regulatory role for miRNA: miRNA duplexes. RNA 2004;10(2):171–5. PMID: 14730015.Liao J.-Y., Ma L.-M., Guo Y.-H. et al. Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 39 trailers. PLoS One 2010;5(5):1–14. DOI: 10.1371/journal.pone.0010563. PMID: 20498841.Khudayberdiev S.A., Zampa F., Rajman M., Schratt G. A comprehensive characterization of the nuclear microRNA repertoire of post-mitotic neurons. Front Mol Neurosci 2013;6(43):1–19. DOI: 10.3389/fnmol.2013.00043. PMID: 24324399.Huang H.Y., Chien C.H., Jen K.H., Huang H.D. RegRNA: an integrated web server for identifying regulatory RNA motifs and elements. Nucl Aci Res 2006;34. DOI: 10.1093/nar/gkl333. PMID: 16845041.Gu X., Mooers B.H., Thomas L.M. et al. Structures and energetics of four adjacent G·U pairs that stabilize an RNA helix. J Phys Chem B 2015;119(42):13252–61. DOI: 10.1021/acs.jpcb.5b06970. PMID: 26425937.Mathews D.H., Disney M.D., Childs J.L. et al. Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure. Proc Natl Acad Sci USA 2004;101(19):7287–92. DOI: 10.1073/pnas.0401799101. PMID: 15123812.Chen P.S., Su J.L., Cha S.T. et al. miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans. J Clin Invest 2011;121(9): 3442–55. DOI: 10.1172/JCI45390. PMID: 21841313.Wong J.J., Ritchie W., Gao D. et al. Identification of nuclear-enriched miRNAs during mouse granulopoiesis. J Hematol Oncol 2014;7(42):1–15. DOI: 10.1186/1756-8722-7-42. PMID: 24886830.Kushlinskiy N.E., Friedman M.V., Braga E.A. Molecular mechanisms and microRNAs in the pathogenesis of osteosarcoma. Biokhimiya = Biochemistry 2016;81(4):448–64. (In Russ.)Кушлинский Н.Е., Фридман М.В., Брага Э.А. Молекулярные механизмы и микроРНК в патогенезе остеосаркомы. Биохимия 2016;81(4):448–64.Shu J., Xia Z., Li L. et al. Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17–92 cluster microRNAs. RNA Biol 2012;9(10):1275–87. DOI: 10.4161/rna.21998. PMID: 22995834.Pitchiaya S., Heinicke L.A., Park J.I. et al. Resolving subcellular miRNA trafficking and turnover at single-molecule resolution. Cell Report 2017;19:630–42. DOI: 10.1016/j.celrep.2017.03.075. PMID: 28423324.Korla K., Arrigo P., Mitra C.K. Promotors, toll like receptors and microRNAs: A strange association. Indian J Biochem Biophys 2013;50(3):169–76. PMID: 23898479.Hwang H.W., Wentzel E.A., Mendell J.T. A hexanucleotide element directs microRNA nuclear import. Science 2007;315(5808):97–100. DOI: 10.1126/science.1136235. PMID: 17204650.Wang B., Bao L. Axonal microRNAs: localization, function and regulatory mechanism during axon development. J Mol Cell Biol 2017;9(2):82–90. DOI: 10.1093/jmcb/mjw050. PMID: 27932485.