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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Advances in Molecular Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Advances in Molecular Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Успехи молекулярной онкологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-805X</issn><issn publication-format="electronic">2413-3787</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">207</article-id><article-id pub-id-type="doi">10.17650/2313-805X-2019-6-1-57-62</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Features of some transcription factors gene expression in the malignancy tissues of the corpus uteri</article-title><trans-title-group xml:lang="ru"><trans-title>Особенности экспрессии генов некоторых транскрипционных факторов при малигнизации тканей тела матки</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8942-3733</contrib-id><name-alternatives><name xml:lang="en"><surname>Kutilin</surname><given-names>D. S.</given-names></name><name xml:lang="ru"><surname>Кутилин</surname><given-names>Д. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>63 14<sup>th</sup> Line, Rostov-on-Don 344037.</p></bio><bio xml:lang="ru"><p>Кутилин Денис Сергеевич.</p><p>344037 Ростов-на-Дону, 14-я линия, 63.</p></bio><email>k.denees@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nikitin</surname><given-names>I. S.</given-names></name><name xml:lang="ru"><surname>Никитин</surname><given-names>И. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>63 14<sup>th</sup> Line, Rostov-on-Don 344037.</p></bio><bio xml:lang="ru"><p>344037 Ростов-на-Дону, 14-я линия, 63.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3061-6108</contrib-id><name-alternatives><name xml:lang="en"><surname>Kit</surname><given-names>O. I.</given-names></name><name xml:lang="ru"><surname>Кит</surname><given-names>О. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>63 14<sup>th</sup> Line, Rostov-on-Don 344037.</p></bio><bio xml:lang="ru"><p>344037 Ростов-на-Дону, 14-я линия, 63.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Rostov Research Institute of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Ростовский научно-исследовательский онкологический институт Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-01-15" publication-format="electronic"><day>15</day><month>01</month><year>2019</year></pub-date><volume>6</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>57</fpage><lpage>62</lpage><history><date date-type="received" iso-8601-date="2019-04-28"><day>28</day><month>04</month><year>2019</year></date><date date-type="accepted" iso-8601-date="2019-04-28"><day>28</day><month>04</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Kutilin D.S., Nikitin I.S., Kit O.I.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, Кутилин Д.С., Никитин И.С., Кит О.И.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Kutilin D.S., Nikitin I.S., Kit O.I.</copyright-holder><copyright-holder xml:lang="ru">Кутилин Д.С., Никитин И.С., Кит О.И.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://umo.abvpress.ru/jour/article/view/207">https://umo.abvpress.ru/jour/article/view/207</self-uri><abstract xml:lang="en"><p/></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>gene expression</kwd><kwd>transcription factor</kwd><kwd>pluripotency</kwd><kwd>corpus uteri cancer</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>экспрессия генов</kwd><kwd>транскрипционный фактор</kwd><kwd>плюрипотентность</kwd><kwd>рак тела матки</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Kit O.I., Vodolazhsky D.I., Kutilin D.S. Aberrant transcriptional activity of apoptosis-regulating genes in malignant neoplasm of corpus uteri. Molekulyarnaya meditsina = Molecular Medicine 2018;16(1):25—31 (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Кит О.И., Водолажский Д.И., Кутилин Д.С. и др. Аберрантная транскрипционная активность апоптоз-регулирующих генов при малигнизации тканей тела матки. Молекулярная медицина 2018;16(1):25—32. DOI: 10.29296/24999490-2018-01-05.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><mixed-citation>Pitynski K., Banas T., Pietrus M. et al. SOX-2, but not Oct4, is highly expressed in early-stage endometrial adenocarcinoma and is related to tumour grading. Int J Clin Exp Pathol 2015;8(7):8189—98.</mixed-citation></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Kit O.I., Vodolazhsky D.I., Kutilin D.S. et al. Changes in expression of estrogen-regulatory genes in malignancy uterine tis¬sues. Kubanskiy nauchnyy meditsinskiy vestnik = Kuban Scientific Medical Bulletin 2016;(2):84—90. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Кит О.И., Водолажский Д.И., Кутилин Д.С. и др. Изменение экспрессии эстроген-регуляторных генов при малигнизации тканей тела матки. Кубанский научный медицинский вестник 2016;157(2):84—90. DOI: 10.25207/1608-6228-2016-2-84-90.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><mixed-citation>Zhu C.Q., Shih W., Ling C.H., Tsao M.S. Immunohistochemical markers of prognosis in non-small cell lung cancer: a review and proposal for a multiphase approach to marker evaluation. J Clin Pathol 2006;59(8):790-800. DOI: 10.1136/jcp.2005.031351. PMID: 16873561.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Chen Z., Xu W.R., Qian H. et al. Oct4, a novel marker for human gastric cancer. J Surg Oncol 2009;99(7):414—19. DOI: 10.1002/jso.21270. PMID: 19347886.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Masui S., Nakatake Y., Toyooka Y. et al. Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 2007;9(6):625—35. DOI: 10.1038/ncb1589. PMID: 17515932.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Gearhart J., Pashos E.E., Prasad M.K. Pluripotency redux — advances in stem-cell research. N Engl J Med 2007;357(15):1469—72. DOI: 10.1056/NEJMp078126. PMID: 17928593.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Chen Y., McGee J., Chen X. et al. Identification of druggable cancer driver genes amplified across T CGA datasets. PLoS One 2014;9(5):e98293. DOI: 10.1371/journal.pone.0107646. PMID: 24874471.</mixed-citation></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Kit O.I., Vodolazhsky D.I., Kutilin D.S. et al. Method of recurrent endometrial cancer prediction based on PTEN and CYP1B1 genes expression level. Patent for invention RUS 2605302, 10.11.2015. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Кит О.И., Водолажский Д.И., Кутилин Д.С. и др. Способ прогнозирования рецидивов рака тела матки на основании уровня экспрессии генов PTENи CYP1B1. Патент на изобретение RUS 2605302, 10.11.2015.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Kutilin D.S. Molecular mechanisms for the implementation of geroprotective activity of the delta-sleep peptide. Author’s abstract of thesis ... of candidate iological sciences: 03.01.04. South Federal University. Rostov-on-Don, 2013. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Кутилин Д.С. Молекулярные механизмы реализации геропротекторной активности пептида дельта-сна. Автореф. дис. ... канд. биол. наук: 03.01.04. Южный федеральный университет. Ростов-на-Дону, 2013.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Kit O.I., Vodolazhsky D.I., Dimitriadi S.N. et al. The activity of proapoptotic genes increases after renal ischemia/reperfusion. Molekulyarnaya biologiya = Molecular Biology 2017;51(3):445—52. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Кит О.И., Водолажский Д.И., Димитриади С.Н. и др. Активность проапоптотических генов повышается после ишемии/реперфузии почки. Молекулярная биология 2017;51(3):502—11. DOI: 10.7868/S0026898417030090.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><mixed-citation>Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25(4):402-8. DOI: 10.1006/meth.2001.1262. PMID: 11846609.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Hubbard S., Gargett C. A cancer stem cell origin for human endometrial carcinoma? Reproduction 2010;140(1):23—32. DOI: 10.1530/REP-09-0411. PMID: 20089663.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126(4):663-76. DOI: 10.1016/j.cell.2006.07.024. PMID: 16904174.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Rizzino A. The Sox2-Oct4 connection: critical players in a much larger interdependent network integrated at multiple levels. Stem Cells 2013;31(6):1033—9. DOI: 10.1002/stem.1352. PMID: 23401375.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>You L., Guo X., Huang Y. Correlation of cancer stem-cell markers OCT4, SOX2, and NANOG with clinicopathological features and prognosis in operative patients with rectal cancer. Yonsei Med J 2017;59(1):35—42. DOI: 10.3349/ymj.2018.59.1.35. PMID: 29214774.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Hatefi N., Nouraee N., Parvin M. et al. Evaluating the expression of OCT4 as a prognostic tumor marker in bladder cancer. Iran J Basic Med Sci 2012;15(6):1154—61. PMID: 23653844.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Lee C.J., Sung P.L., Kuo M.H. et al. Crosstalk between SOX2 and cytokine signaling in endometrial carcinoma. Sci Rep 2018;8(1):17550. DOI: 10.1038/s41598-018-35592-0. PMID: 30510261.</mixed-citation></ref></ref-list></back></article>
