Двуликий Янус: к 150-летию открытия ДДТ
https://doi.org/10.17650/2313-805X-2024-11-3-41-55
Аннотация
Одним из факторов, ассоциированных с ростом заболеваемости злокачественными новообразованиями, является загрязнение окружающей среды канцерогенными соединениями, в том числе пестицидами. Стойкий органический загрязнитель инсектицид дихлордифенилтрихлорэтан (ДДТ) до недавнего времени был безальтернативным средством для борьбы с переносчиками малярии. Несмотря на многочисленные доказательства негативного действия на здоровье человека, ДДТ и в настоящее время используется в некоторых странах.
Цель обзора – всесторонний анализ динамики применения пестицида ДДТ и влияния последствий его использования на сферу глобального здравоохранения, а также исследование механизмов его действия на организм человека, включая влияние на эндокринную систему и канцерогенные эффекты.
При подготовке обзора использованы базы биомедицинской литературы PubMed (2853 публикации), Elsivier (3139 публикаций), eLibrary (784 публикации), а для получения полнотекстовых документов – электронные ресурсы PubMed Central (PMC), Science Direct, Research Gate, КиберЛенинка.
Ключевые слова
Об авторах
О. В. МорозоваРоссия
115522 Москва, Каширское шоссе, 24
А. Ю. Букина
Россия
115522 Москва, Каширское шоссе, 24
119454 Москва, пр-кт Вернадского, 78
В. Г. Попова
Россия
115522 Москва, Каширское шоссе, 24
Г. И. Хайриева
Россия
119991 Москва, ул. Трубецкая, 8, стр. 2
Г. Р. Сагитова
Россия
119991 Москва, ул. Трубецкая, 8, стр. 2
Г. А. Белицкий
Россия
115522 Москва, Каширское шоссе, 24
М. Г. Якубовская
Россия
115522 Москва, Каширское шоссе, 24
К. И. Кирсанов
Россия
115522 Москва, Каширское шоссе, 24
117198 Москва, ул. Миклухо-Маклая, 6
В. П. Максимова
Россия
Варвара Павловна Максимова
115522 Москва, Каширское шоссе, 24
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Рецензия
Для цитирования:
Морозова О.В., Букина А.Ю., Попова В.Г., Хайриева Г.И., Сагитова Г.Р., Белицкий Г.А., Якубовская М.Г., Кирсанов К.И., Максимова В.П. Двуликий Янус: к 150-летию открытия ДДТ. Успехи молекулярной онкологии. 2024;11(3):41-55. https://doi.org/10.17650/2313-805X-2024-11-3-41-55
For citation:
Morozova O.V., Bukina A.Yu., Popova V.G., Khairieva G.I., Sagitova G.R., Belitsky G.A., Yakubovskaya M.G., Kirsanov K.I., Maksimova V.P. Two-faced Janus: on the 150th anniversary of the discovery of DDT. Advances in Molecular Oncology. 2024;11(3):41-55. (In Russ.) https://doi.org/10.17650/2313-805X-2024-11-3-41-55