Email this article Modern conceptions of serological tumor markers and their role in oncology
- Authors: Sergeeva N.S.1, Marshutina N.V.1, Solokhina M.P.1, Alentov I.I.1, Parilova N.K.1, Zenkina E.V.1, Skashchkova T.E.2
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Affiliations:
- P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia
- N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow
- Issue: Vol 1, No 1 (2014)
- Pages: 69-80
- Section: REVIEW ARTICLES
- Published: 02.06.2015
- URL: https://umo.abvpress.ru/jour/article/view/18
- DOI: https://doi.org/10.17650/2313-805X.2014.1.1.69-80
- ID: 18
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Abstract
The paper reviews modern concepts of serological tumor markers and their place in oncology: using for differential diagnostics, in the prognosis of the tumor, follow-up and for preclinical revealing of relapses, as well as in the screening aimed at early detection of malignant neoplasms. Biochemical characteristics and functions of most informative tumor markers (CA125, PSA etc.) were described. Currently diagnostic indexes, obtained by the in vitro diagnostic multivariate index assay (IVDMIA), and algorithms using several serological markers begin to apply in laboratory practice to increase diagnostic accuracy. Also some promising new serological tumor markers were described in this review.
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About the authors
N. S. Sergeeva
P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia
Author for correspondence.
Email: prognoz.06@mail.ru
Russian Federation
N. V. Marshutina
P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia
Email: fake@neicon.ru
Russian Federation
M. P. Solokhina
P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia
Email: fake@neicon.ru
Russian Federation
I. I. Alentov
P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia
Email: fake@neicon.ru
Russian Federation
N. K. Parilova
P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia
Email: fake@neicon.ru
Russian Federation
E. V. Zenkina
P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia
Email: fake@neicon.ru
Russian Federation
T. E. Skashchkova
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow
Email: fake@neicon.ru
Russian Federation
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